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Spaceflight-induced vertebral bone loss in ovariectomized rats is associated with increased bone marrow adiposity and no change in bone formation
There is often a reciprocal relationship between bone marrow adipocytes and osteoblasts, suggesting that marrow adipose tissue (MAT) antagonizes osteoblast differentiation. MAT is increased in rodents during spaceflight but a causal relationship between MAT and bone loss remains unclear. In the pres...
Autores principales: | Keune, Jessica A, Philbrick, Kenneth A, Branscum, Adam J, Iwaniec, Urszula T, Turner, Russell T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515514/ https://www.ncbi.nlm.nih.gov/pubmed/28725730 http://dx.doi.org/10.1038/npjmgrav.2016.16 |
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