3,3′,4,4′,5-Pentachlorobiphenyl Inhibits Drug Efflux Through P-Glycoprotein in KB-3 Cells Expressing Mutant Human P-Glycoprotein

The effects on the drug efflux of 3,3′,4,4′,5-pentachlorobiphenyl (PCB-126), the most toxic of all coplanar polychlorinated biphenyls (Co-PCBs), were examined in KB-3 cells expressing human wild-type and mutant P-glycoprotein in which the 61st amino acid was substituted for serine or phenylalanine (...

Descripción completa

Detalles Bibliográficos
Autores principales: Fujise, Hiroshi, Sasawatari, Shigemi, Annoura, Takeshi, Ikeda, Teruo, Ueda, Kazumitsu
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC551584/
https://www.ncbi.nlm.nih.gov/pubmed/15292579
http://dx.doi.org/10.1155/S1110724304308028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC551584/
https://www.ncbi.nlm.nih.gov/pubmed/15292579
http://dx.doi.org/10.1155/S1110724304308028

Ejemplares similares