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Loss of IRF2BP2 in Microglia Increases Inflammation and Functional Deficits after Focal Ischemic Brain Injury

Ischemic stroke causes neuronal cell death and triggers a cascade of inflammatory signals that contribute to secondary brain damage. Microglia, the brain-resident macrophages that remove dead neurons, play a critical role in the brain’s response to ischemic injury. Our previous studies showed that I...

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Detalles Bibliográficos
Autores principales: Cruz, Shelly A., Hari, Aswin, Qin, Zhaohong, Couture, Pascal, Huang, Hua, Lagace, Diane C., Stewart, Alexandre F. R., Chen, Hsiao-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515910/
https://www.ncbi.nlm.nih.gov/pubmed/28769762
http://dx.doi.org/10.3389/fncel.2017.00201