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Physiological stress-induced corticosterone increases heme uptake via KLF4-HCP1 signaling pathway in hippocampus neurons

Iron overload has attracted much attention because of its adverse effect in increasing the risk of developing several neurodegenerative disorders. Under various pathologic conditions, a lot of heme are released. The aggregation of heme is more neurotoxic than that of iron released from the heme brea...

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Detalles Bibliográficos
Autores principales: Li, Hongxia, Zhang, Caixia, Shen, Hui, Shen, Zhilei, Wu, Lusha, Mo, Fengfeng, Li, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515979/
https://www.ncbi.nlm.nih.gov/pubmed/28720846
http://dx.doi.org/10.1038/s41598-017-06058-6