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Iron overload exacerbates age-associated cardiac hypertrophy in a mouse model of hemochromatosis
Cardiac damage associated with iron overload is the most common cause of morbidity and mortality in patients with hereditary hemochromatosis, but the precise mechanisms leading to disease progression are largely unexplored. Here we investigated the effects of iron overload and age on cardiac hypertr...
Autores principales: | Sukumaran, Abitha, Chang, JuOae, Han, Murui, Mintri, Shrutika, Khaw, Ban-An, Kim, Jonghan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516030/ https://www.ncbi.nlm.nih.gov/pubmed/28720890 http://dx.doi.org/10.1038/s41598-017-05810-2 |
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