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Identification of a new family of putative PD-(D/E)XK nucleases with unusual phylogenomic distribution and a new type of the active site

BACKGROUND: Prediction of structure and function for uncharacterized protein families by identification of evolutionary links to characterized families and known structures is one of the cornerstones of genomics. Theoretical assignment of three-dimensional folds and prediction of protein function ev...

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Detalles Bibliográficos
Autores principales: Feder, Marcin, Bujnicki, Janusz M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC551604/
https://www.ncbi.nlm.nih.gov/pubmed/15720711
http://dx.doi.org/10.1186/1471-2164-6-21