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Engineered G protein coupled receptors reveal independent regulation of internalization, desensitization and acute signaling

BACKGROUND: The physiological regulation of G protein-coupled receptors, through desensitization and internalization, modulates the length of the receptor signal and may influence the development of tolerance and dependence in response to chronic drug treatment. To explore the importance of receptor...

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Detalles Bibliográficos
Autores principales:	Scearce-Levie, Kimberly, Lieberman, Michael D, Elliott, Heather H, Conklin, Bruce R
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC551613/ https://www.ncbi.nlm.nih.gov/pubmed/15707483 http://dx.doi.org/10.1186/1741-7007-3-3

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