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Functional outcome after surgery in patients with bone sarcoma around the knee; results from a long‐term prospective study

BACKGROUND AND OBJECTIVES: In a previous conducted study functional outcome of young patients with bone sarcoma located around the knee was longitudinally evaluated during the first 2 years postoperatively. Functional outcome improved significantly over the first 2 years. The purpose of this descrip...

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Autores principales: van Egmond‐van Dam, Janneke C., Bekkering, W. Peter, Bramer, Jos A.M., Beishuizen, Auke, Fiocco, Marta, Dijkstra, P.D. Sander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516165/
https://www.ncbi.nlm.nih.gov/pubmed/28384378
http://dx.doi.org/10.1002/jso.24618
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author van Egmond‐van Dam, Janneke C.
Bekkering, W. Peter
Bramer, Jos A.M.
Beishuizen, Auke
Fiocco, Marta
Dijkstra, P.D. Sander
author_facet van Egmond‐van Dam, Janneke C.
Bekkering, W. Peter
Bramer, Jos A.M.
Beishuizen, Auke
Fiocco, Marta
Dijkstra, P.D. Sander
author_sort van Egmond‐van Dam, Janneke C.
collection PubMed
description BACKGROUND AND OBJECTIVES: In a previous conducted study functional outcome of young patients with bone sarcoma located around the knee was longitudinally evaluated during the first 2 years postoperatively. Functional outcome improved significantly over the first 2 years. The purpose of this descriptive study was to evaluate the functional outcome of these patients at long‐term follow‐up of 7 years. METHODS: Functional outcome was assessed with the TESS, MSTS, Baecke questionnaire, and three functional performance tests: time up and down stairs (TUDS), various walking activities (VWA), and the 6‐min walking test (6MWT). Linear Mixed Model has been employed for the repeated measurements. RESULTS: Twenty patients of the original study (n = 44) participated in the current study. Fifteen limb‐salvage and five ablative surgery patients, median follow‐up 7.4 years (6.8‐8.0) (CI 95%), mean age 22.3 years (18.2‐31.6). Between 2 and 7 years after surgery, 8 limb‐salvage patients (53%) encountered surgery related complications. Questionnaires and functional performance tests showed no significant difference in functional outcome between 2 years and 7 years after surgery (P < 0.05). CONCLUSIONS: Between 2 years and follow‐up at average 7 years after surgery no further improvements were noticed at young patients with a bone sarcoma located around the knee.
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spelling pubmed-55161652017-08-02 Functional outcome after surgery in patients with bone sarcoma around the knee; results from a long‐term prospective study van Egmond‐van Dam, Janneke C. Bekkering, W. Peter Bramer, Jos A.M. Beishuizen, Auke Fiocco, Marta Dijkstra, P.D. Sander J Surg Oncol Research Articles BACKGROUND AND OBJECTIVES: In a previous conducted study functional outcome of young patients with bone sarcoma located around the knee was longitudinally evaluated during the first 2 years postoperatively. Functional outcome improved significantly over the first 2 years. The purpose of this descriptive study was to evaluate the functional outcome of these patients at long‐term follow‐up of 7 years. METHODS: Functional outcome was assessed with the TESS, MSTS, Baecke questionnaire, and three functional performance tests: time up and down stairs (TUDS), various walking activities (VWA), and the 6‐min walking test (6MWT). Linear Mixed Model has been employed for the repeated measurements. RESULTS: Twenty patients of the original study (n = 44) participated in the current study. Fifteen limb‐salvage and five ablative surgery patients, median follow‐up 7.4 years (6.8‐8.0) (CI 95%), mean age 22.3 years (18.2‐31.6). Between 2 and 7 years after surgery, 8 limb‐salvage patients (53%) encountered surgery related complications. Questionnaires and functional performance tests showed no significant difference in functional outcome between 2 years and 7 years after surgery (P < 0.05). CONCLUSIONS: Between 2 years and follow‐up at average 7 years after surgery no further improvements were noticed at young patients with a bone sarcoma located around the knee. John Wiley and Sons Inc. 2017-04-06 2017-06-15 /pmc/articles/PMC5516165/ /pubmed/28384378 http://dx.doi.org/10.1002/jso.24618 Text en © 2017 The Authors. Journal of Surgical Oncology Published by Wiley Periodicals, Inc. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Research Articles
van Egmond‐van Dam, Janneke C.
Bekkering, W. Peter
Bramer, Jos A.M.
Beishuizen, Auke
Fiocco, Marta
Dijkstra, P.D. Sander
Functional outcome after surgery in patients with bone sarcoma around the knee; results from a long‐term prospective study
title Functional outcome after surgery in patients with bone sarcoma around the knee; results from a long‐term prospective study
title_full Functional outcome after surgery in patients with bone sarcoma around the knee; results from a long‐term prospective study
title_fullStr Functional outcome after surgery in patients with bone sarcoma around the knee; results from a long‐term prospective study
title_full_unstemmed Functional outcome after surgery in patients with bone sarcoma around the knee; results from a long‐term prospective study
title_short Functional outcome after surgery in patients with bone sarcoma around the knee; results from a long‐term prospective study
title_sort functional outcome after surgery in patients with bone sarcoma around the knee; results from a long‐term prospective study
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516165/
https://www.ncbi.nlm.nih.gov/pubmed/28384378
http://dx.doi.org/10.1002/jso.24618
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