Potential mechanisms of Zika‐linked microcephaly

A recent outbreak of Zika virus (ZIKV) in Brazil is associated with microcephaly in infants born of infected mothers. As this pandemic spreads, rapid scientific investigation is shedding new light on how prenatal infection with ZIKV causes microcephaly. In this analysis we provide an overview of bot...

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Detalles Bibliográficos
Autores principales: Merfeld, Emily, Ben‐Avi, Lily, Kennon, Mason, Cerveny, Kara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2017
Materias:
Primer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516183/
https://www.ncbi.nlm.nih.gov/pubmed/28383800
http://dx.doi.org/10.1002/wdev.273
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author Merfeld, Emily
Ben‐Avi, Lily
Kennon, Mason
Cerveny, Kara L.
author_facet Merfeld, Emily
Ben‐Avi, Lily
Kennon, Mason
Cerveny, Kara L.
author_sort Merfeld, Emily
collection PubMed
description A recent outbreak of Zika virus (ZIKV) in Brazil is associated with microcephaly in infants born of infected mothers. As this pandemic spreads, rapid scientific investigation is shedding new light on how prenatal infection with ZIKV causes microcephaly. In this analysis we provide an overview of both microcephaly and ZIKV, explore the connection between prenatal ZIKV infection and microcephaly, and highlight recent insights into how prenatal ZIKV infection depletes the pool of neural progenitors in the developing brain. WIREs Dev Biol 2017, 6:e273. doi: 10.1002/wdev.273 For further resources related to this article, please visit the WIREs website.
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spelling pubmed-55161832017-08-02 Potential mechanisms of Zika‐linked microcephaly Merfeld, Emily Ben‐Avi, Lily Kennon, Mason Cerveny, Kara L. Wiley Interdiscip Rev Dev Biol Primer A recent outbreak of Zika virus (ZIKV) in Brazil is associated with microcephaly in infants born of infected mothers. As this pandemic spreads, rapid scientific investigation is shedding new light on how prenatal infection with ZIKV causes microcephaly. In this analysis we provide an overview of both microcephaly and ZIKV, explore the connection between prenatal ZIKV infection and microcephaly, and highlight recent insights into how prenatal ZIKV infection depletes the pool of neural progenitors in the developing brain. WIREs Dev Biol 2017, 6:e273. doi: 10.1002/wdev.273 For further resources related to this article, please visit the WIREs website. John Wiley & Sons, Inc. 2017-04-06 2017 /pmc/articles/PMC5516183/ /pubmed/28383800 http://dx.doi.org/10.1002/wdev.273 Text en © 2017 The Authors. WIREs Developmental Biology published by Wiley Periodicals, Inc. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Primer
Merfeld, Emily
Ben‐Avi, Lily
Kennon, Mason
Cerveny, Kara L.
Potential mechanisms of Zika‐linked microcephaly
title Potential mechanisms of Zika‐linked microcephaly
title_full Potential mechanisms of Zika‐linked microcephaly
title_fullStr Potential mechanisms of Zika‐linked microcephaly
title_full_unstemmed Potential mechanisms of Zika‐linked microcephaly
title_short Potential mechanisms of Zika‐linked microcephaly
title_sort potential mechanisms of zika‐linked microcephaly
topic Primer
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516183/
https://www.ncbi.nlm.nih.gov/pubmed/28383800
http://dx.doi.org/10.1002/wdev.273
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