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A small-molecule/cytokine combination enhances hematopoietic stem cell proliferation via inhibition of cell differentiation
BACKGROUND: Accumulated evidence supports the potent stimulating effects of multiple small molecules on the expansion of hematopoietic stem cells (HSCs) which are important for the therapy of various hematological disorders. Here, we report a novel, optimized formula, named the SC cocktail, which co...
Autores principales: | Wang, Lan, Guan, Xin, Wang, Huihui, Shen, Bin, Zhang, Yu, Ren, Zhihua, Ma, Yupo, Ding, Xinxin, Jiang, Yongping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516306/ https://www.ncbi.nlm.nih.gov/pubmed/28720126 http://dx.doi.org/10.1186/s13287-017-0625-z |
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