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A small-molecule/cytokine combination enhances hematopoietic stem cell proliferation via inhibition of cell differentiation

BACKGROUND: Accumulated evidence supports the potent stimulating effects of multiple small molecules on the expansion of hematopoietic stem cells (HSCs) which are important for the therapy of various hematological disorders. Here, we report a novel, optimized formula, named the SC cocktail, which co...

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Detalles Bibliográficos
Autores principales: Wang, Lan, Guan, Xin, Wang, Huihui, Shen, Bin, Zhang, Yu, Ren, Zhihua, Ma, Yupo, Ding, Xinxin, Jiang, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516306/
https://www.ncbi.nlm.nih.gov/pubmed/28720126
http://dx.doi.org/10.1186/s13287-017-0625-z

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