Cargando…

Association of GCLM -588C/T and GCLC -129T/C Promoter Polymorphisms of Genes Coding the Subunits of Glutamate Cysteine Ligase with Ischemic Heart Disease Development in Kazakhstan Population

BACKGROUND: Glutamate cysteine ligase (GCL) is a rate-limiting enzyme in synthesis of glutathione. Evidence suggests that genetic variations in the promoter region of genes coding a catalytic subunit (GCLC -129T/C) and a modifier subunit (GCLM -588C/T) of GCL have a functional impact on their transc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Skvortsova, Liliya, Perfelyeva, Anastasia, Khussainova, Elmira, Mansharipova, Alma, Forman, Henry Jay, Djansugurova, Leyla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516751/ https://www.ncbi.nlm.nih.gov/pubmed/28757675 http://dx.doi.org/10.1155/2017/4209257

Ejemplares similares

Integrative Functional Genomic Analysis in Multiplex Autism Families from Kazakhstan
por: Perfilyeva, Anastassiya, et al.
Publicado: (2022)

Associations of GCLM, gclc and GSTP1 gene polymorphisms and antituberculosis drugs-induced hepatitis
por: Kim, Sang-Heon, et al.
Publicado: (2015)

The Determination of Genetic Markers of Age-Related Cancer Pathologies in Populations from Kazakhstan
por: Djansugurova, Leyla B., et al.
Publicado: (2013)

Polymorphism in glutamate cysteine ligase catalytic subunit (GCLC) is associated with sulfamethoxazole-induced hypersensitivity in HIV/AIDS patients
por: Wang, Danxin, et al.
Publicado: (2012)

Genetic Relationship Among the Kazakh People Based on Y-STR Markers Reveals Evidence of Genetic Variation Among Tribes and Zhuz
por: Khussainova, Elmira, et al.
Publicado: (2022)

Association of genetic variants in the promoter region of genes encoding p22phox (CYBA) and glutamate cysteine ligase catalytic subunit (GCLC) and renal disease in patients with type 1 diabetes mellitus
por: Vieira, Suzana M, et al.
Publicado: (2011)

Downregulation of LncRNA GCLC-1 Promotes Microcystin-LR-Induced Malignant Transformation of Human Liver Cells by Regulating GCLC Expression
por: Huang, Xinglei, et al.
Publicado: (2023)

Persistence of improved glucose homeostasis in Gclm null mice with age and cadmium treatment
por: Schaupp, Christopher M., et al.
Publicado: (2021)

Individual Risk Assessment for Population Living on the Territories Long-Term Polluted by Organochlorine Pesticides
por: Garshin, Aleksandr, et al.
Publicado: (2023)

Structural Basis of Cysteine Ligase MshC Inhibition by Cysteinyl-Sulfonamides
por: Pang, Luping, et al.
Publicado: (2022)

Behavioral Characterization of GCLM-Knockout Mice, a Model for Enhanced Susceptibility to Oxidative Stress
por: Cole, Toby B., et al.
Publicado: (2011)

From Data to Causes III: Bayesian Priors for General Cross-Lagged Panel Models (GCLM)
por: Zyphur, Michael J., et al.
Publicado: (2021)

Run 796, 26.588 GeV/c, 10.1.77, Run 805, 26.588 GeV/c, 26.1.77, Run 823, 26.588 GeV/c, 17.3.77, Measurement of the magnetic hysteresis of the CR's and correction of its effect on the closed orbits
por: Wyss, C
Publicado: (1977)

Systematical analysis of ferroptosis regulators and identification of GCLM as a tumor promotor and immunological biomarker in bladder cancer
por: Wang, Song, et al.
Publicado: (2022)

No Association between the rs1799836 Polymorphism of the Monoamine Oxidase B Gene and the Risk of Autism Spectrum Disorders in the Kazakhstani Population
por: Perfilyeva, Anastassiya V., et al.
Publicado: (2019)

Alterations in TRN-anterodorsal thalamocortical circuits affect sleep architecture and homeostatic processes in oxidative stress vulnerable Gclm(−/−) mice
por: Czekus, Christina, et al.
Publicado: (2022)

Analysis of GABRG2 C588T polymorphism in genetic epilepsy and evaluation of GABRG2 in drug treatment
por: Wang, Shitao, et al.
Publicado: (2021)

588. Are Popliteal Vein PICCs safe for Neonates?
por: Lochner, Harold J, et al.
Publicado: (2019)

Memo to the T.C. Committee on the T129 experiment
por: CERN. Geneva. Track Chamber Committee
Publicado: (1966)

Exercise induced upregulation of glutamate-cysteine ligase catalytic subunit and glutamate-cysteine ligase modifier subunit gene expression in Thoroughbred horses
por: Park, Jeong-Woong, et al.
Publicado: (2017)

The influence of pro-longevity gene Gclc overexpression on the age-dependent changes in Drosophila transcriptome and biological functions
por: Moskalev, Alexey, et al.
Publicado: (2016)

The Neuronal Overexpression of Gclc in Drosophila melanogaster Induces Life Extension With Longevity-Associated Transcriptomic Changes in the Thorax
por: Moskalev, Alexey, et al.
Publicado: (2019)

Mitochondrial “power” drives tamoxifen resistance: NQO1 and GCLC are new therapeutic targets in breast cancer
por: Fiorillo, Marco, et al.
Publicado: (2017)

High GCLC level in tumor tissues is associated with poor prognosis of hepatocellular carcinoma after curative resection
por: Sun, Jialei, et al.
Publicado: (2019)

Ferroptosis-Related Gene GCLC Is a Novel Prognostic Molecular and Correlates with Immune Infiltrates in Lung Adenocarcinoma
por: Luo, Lianxiang, et al.
Publicado: (2022)

Polymorphisms of the GCLC Gene Are Novel Genetic Markers for Susceptibility to Psoriasis Associated with Alcohol Abuse and Cigarette Smoking
por: Efanova, Ekaterina, et al.
Publicado: (2023)

GGT1 Suppresses the Development of Ferroptosis and Autophagy in Mouse Retinal Ganglion Cell Through Targeting GCLC
por: Xu, Guihua, et al.
Publicado: (2023)

Run 609 - 30 May 1975, Ring 1 - 26.588 GeV/c, Matching tolerances
por: Autin, B, et al.
Publicado: (1975)

GABRG2 C588T Polymorphism Is Associated with Idiopathic Generalized Epilepsy but Not with Antiepileptic Drug Resistance in Pakistani Cohort
por: Saleem, Tayyaba, et al.
Publicado: (2022)

Metagenomic Exploration of Koumiss from Kazakhstan
por: Bogoyavlenskiy, Andrey, et al.
Publicado: (2022)

Population-based Prostate Cancer Screening in Kazakhstan
por: ISHKININ, Yevgeniy, et al.
Publicado: (2017)

Prevalence of Viral Hepatitis B, C, and D in Kazakhstan
por: Jumabayeva, Almagul, et al.
Publicado: (2022)

The E3 Ubiquitin Ligase TMEM129 Is a Tri-Spanning Transmembrane Protein
por: van de Weijer, Michael L., et al.
Publicado: (2016)

The Glutathione Synthesis Gene Gclm Modulates Amphiphilic Polymer-Coated CdSe/ZnS Quantum Dot–Induced Lung Inflammation in Mice
por: McConnachie, Lisa A., et al.
Publicado: (2013)

MTX-211 Inhibits GSH Synthesis through Keap1/NRF2/GCLM Axis and Exerts Antitumor Effects in Bladder Cancer
por: Hu, Bing, et al.
Publicado: (2023)

The likelihood approach for potential role of “GABRG2 (C588T, C315T) gene polymorphisms” on the poor response to carbamazepine therapy in Pakhtun population of Pakistan
por: Ullah, Shakir, et al.
Publicado: (2022)

Dynamic Modeling of Cost-effectiveness of Rotavirus Vaccination, Kazakhstan
por: Freiesleben de Blasio, Birgitte, et al.
Publicado: (2014)

Tuberous sclerosis complex neuropathology requires glutamate-cysteine ligase
por: Malik, Anna R., et al.
Publicado: (2015)

588 Delayed Diagnosis of Hereditary Angioedema. A Case Report
por: González-Díaz, Sandra, et al.
Publicado: (2012)

miR-588 is a prognostic marker in gastric cancer
por: Chen, Yongyi, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_clkb6ridpbfam83jlpc5ugbm5c