Endophilin2 Interacts with GluA1 to Mediate AMPA Receptor Endocytosis Induced by Oligomeric Amyloid-β

Amyloid-β (Aβ) plays an important role in Alzheimer's disease (AD), as oligomeric Aβ induces loss of postsynaptic AMPA receptors (AMPARs) leading to cognitive deficits. The loss of postsynaptic AMPARs is mediated through the clathrin-dependent endocytosis pathway, in which endophilin2 is one of...

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Detalles Bibliográficos
Autores principales: Zhang, Jifeng, Yin, Yichen, Ji, Zhisheng, Cai, Zhenbin, Zhao, Bo, Li, Jiong, Tan, Minghui, Guo, Guoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516760/
https://www.ncbi.nlm.nih.gov/pubmed/28758034
http://dx.doi.org/10.1155/2017/8197085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516760/
https://www.ncbi.nlm.nih.gov/pubmed/28758034
http://dx.doi.org/10.1155/2017/8197085

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