Genome-wide perturbations by miRNAs map onto functional cellular pathways, identifying regulators of chromatin modifiers

BACKGROUND: Regulation of gene expression by microRNAs (miRNAs) is critical for determining cellular fate and function. Dysregulation of miRNA expression contributes to the development and progression of multiple diseases. miRNA can target multiple mRNAs, making deconvolution of the effects of miRNA...

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Detalles Bibliográficos
Autores principales: Moss, Tyler J, Luo, Zijun, Seviour, Elena G, Sehgal, Vasudha, Lu, Yiling, Hill, Steven M, Rupaimoole, Rajesha, Lee, Ju-Seog, Rodriguez-Aguayo, Cristian, Lopez-Berestein, Gabriel, Sood, Anil K, Azencott, Robert, Gray, Joe W, Mukherjee, Sach, Mills, Gordon B, Ram, Prahlad T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516802/
https://www.ncbi.nlm.nih.gov/pubmed/28725457
http://dx.doi.org/10.1038/npjsba.2015.1

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