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Not just a colourful metaphor: modelling the landscape of cellular development using Hopfield networks

The epigenetic landscape was introduced by Conrad Waddington as a metaphor of cellular development. Like a ball rolling down a hillside is channelled through a succession of valleys until it reaches the bottom, cells follow specific trajectories from a pluripotent state to a committed state. Transcr...

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Detalles Bibliográficos
Autores principales: Fard, Atefeh Taherian, Srihari, Sriganesh, Mar, Jessica C, Ragan, Mark A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516853/
https://www.ncbi.nlm.nih.gov/pubmed/28725466
http://dx.doi.org/10.1038/npjsba.2016.1

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