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Not just a colourful metaphor: modelling the landscape of cellular development using Hopfield networks
The epigenetic landscape was introduced by Conrad Waddington as a metaphor of cellular development. Like a ball rolling down a hillside is channelled through a succession of valleys until it reaches the bottom, cells follow specific trajectories from a pluripotent state to a committed state. Transcr...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516853/ https://www.ncbi.nlm.nih.gov/pubmed/28725466 http://dx.doi.org/10.1038/npjsba.2016.1 |