Failure of BACTEC™ MGIT 960™ to detect Mycobacterium tuberculosis complex within a 42-day incubation period

For the optimal recovery of Mycobacterium tuberculosis from the BACTEC™ Mycobacterium Growth Indicator Tube 960™ system, an incubation period of 42–56 days is recommended by the manufacturer. Due to logistical reasons, it is common practice to follow an incubation period of 42 days. We undertook a r...

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Autores principales: Mahomed, Sharana, Dlamini-Mvelase, Nomonde R., Dlamini, Moses, Mlisana, Koleka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AOSIS 2017
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516912/
https://www.ncbi.nlm.nih.gov/pubmed/28879150
http://dx.doi.org/10.4102/ajlm.v6i1.537
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author Mahomed, Sharana
Dlamini-Mvelase, Nomonde R.
Dlamini, Moses
Mlisana, Koleka
author_facet Mahomed, Sharana
Dlamini-Mvelase, Nomonde R.
Dlamini, Moses
Mlisana, Koleka
author_sort Mahomed, Sharana
collection PubMed
description For the optimal recovery of Mycobacterium tuberculosis from the BACTEC™ Mycobacterium Growth Indicator Tube 960™ system, an incubation period of 42–56 days is recommended by the manufacturer. Due to logistical reasons, it is common practice to follow an incubation period of 42 days. We undertook a retrospective study to document positive Mycobacterium Growth Indicator Tube cultures beyond the 42-day incubation period. In total, 98/110 (89%) were positive for M. tuberculosis complex. This alerted us to M. tuberculosis growth detection failure at 42 days.
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spelling pubmed-55169122017-09-06 Failure of BACTEC™ MGIT 960™ to detect Mycobacterium tuberculosis complex within a 42-day incubation period Mahomed, Sharana Dlamini-Mvelase, Nomonde R. Dlamini, Moses Mlisana, Koleka Afr J Lab Med Brief Reports For the optimal recovery of Mycobacterium tuberculosis from the BACTEC™ Mycobacterium Growth Indicator Tube 960™ system, an incubation period of 42–56 days is recommended by the manufacturer. Due to logistical reasons, it is common practice to follow an incubation period of 42 days. We undertook a retrospective study to document positive Mycobacterium Growth Indicator Tube cultures beyond the 42-day incubation period. In total, 98/110 (89%) were positive for M. tuberculosis complex. This alerted us to M. tuberculosis growth detection failure at 42 days. AOSIS 2017-04-26 /pmc/articles/PMC5516912/ /pubmed/28879150 http://dx.doi.org/10.4102/ajlm.v6i1.537 Text en © 2017. The Authors http://creativecommons.org/licenses/by/2.0/ Licensee: AOSIS. This work is licensed under the Creative Commons Attribution License.
spellingShingle Brief Reports
Mahomed, Sharana
Dlamini-Mvelase, Nomonde R.
Dlamini, Moses
Mlisana, Koleka
Failure of BACTEC™ MGIT 960™ to detect Mycobacterium tuberculosis complex within a 42-day incubation period
title Failure of BACTEC™ MGIT 960™ to detect Mycobacterium tuberculosis complex within a 42-day incubation period
title_full Failure of BACTEC™ MGIT 960™ to detect Mycobacterium tuberculosis complex within a 42-day incubation period
title_fullStr Failure of BACTEC™ MGIT 960™ to detect Mycobacterium tuberculosis complex within a 42-day incubation period
title_full_unstemmed Failure of BACTEC™ MGIT 960™ to detect Mycobacterium tuberculosis complex within a 42-day incubation period
title_short Failure of BACTEC™ MGIT 960™ to detect Mycobacterium tuberculosis complex within a 42-day incubation period
title_sort failure of bactec™ mgit 960™ to detect mycobacterium tuberculosis complex within a 42-day incubation period
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516912/
https://www.ncbi.nlm.nih.gov/pubmed/28879150
http://dx.doi.org/10.4102/ajlm.v6i1.537
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