Cargando…
Dysfunctional GPR40/FFAR1 signaling exacerbates pain behavior in mice
We previously showed that activation of G protein-coupled receptor 40/free fatty acid receptor 1 (GPR40/FFAR1) signaling modulates descending inhibition of pain. In this study, we investigated the involvement of fatty acid-GPR40/FFAR1 signaling in the transition from acute to chronic pain. We used G...
Autores principales: | Nakamoto, Kazuo, Aizawa, Fuka, Miyagi, Kei, Yamashita, Takuya, Mankura, Mitsumasa, Koyama, Yutaka, Kasuya, Fumiyo, Hirasawa, Akira, Kurihara, Takashi, Miyata, Atsuro, Tokuyama, Shogo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516985/ https://www.ncbi.nlm.nih.gov/pubmed/28723961 http://dx.doi.org/10.1371/journal.pone.0180610 |
Ejemplares similares
-
PT640. The dysfunction of brain free fatty acid receptor GPR40/FFAR1 signaling relate to the development of chronic pain
por: Nakamoto, Kazuo, et al.
Publicado: (2016) -
PS04. The changes of emotional behavior in a free fatty acid receptor 1, GPR40/FFAR1, deficient mice
por: Aizawa, Fuka, et al.
Publicado: (2016) -
Hypothalamic GPR40 Signaling Activated by Free Long Chain Fatty Acids Suppresses CFA-Induced Inflammatory Chronic Pain
por: Nakamoto, Kazuo, et al.
Publicado: (2013) -
FFAR1/GPR40 Contributes to the Regulation of Striatal Monoamine Releases and Facilitation of Cocaine-Induced Locomotor Activity in Mice
por: Sadamura, Yuko, et al.
Publicado: (2021) -
Astrocyte Activation in Locus Coeruleus Is Involved in Neuropathic Pain Exacerbation Mediated by Maternal Separation and Social Isolation Stress
por: Nakamoto, Kazuo, et al.
Publicado: (2017)