New library construction method for single-cell genomes

A central challenge in sequencing single-cell genomes is the accurate determination of point mutations, phasing of these mutations, and identifying copy number variations with few assumptions. Ideally, this is accomplished under as low sequencing coverage as possible. Here we report our attempt to m...

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Detalles Bibliográficos
Autores principales: Xi, Larry, Belyaev, Alexander, Spurgeon, Sandra, Wang, Xiaohui, Gong, Haibiao, Aboukhalil, Robert, Fekete, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517011/
https://www.ncbi.nlm.nih.gov/pubmed/28723968
http://dx.doi.org/10.1371/journal.pone.0181163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517011/
https://www.ncbi.nlm.nih.gov/pubmed/28723968
http://dx.doi.org/10.1371/journal.pone.0181163

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