Cargando…
Directed migration of cancer cells by the graded texture of the underlying matrix
Living cells and the extracellular matrix (ECM) can display complex interactions that define key developmental, physiological and pathological processes. Here, we report a new type of directed migration — which we term ‘topotaxis’ — by which cell movement is guided by the gradient of the nanoscale t...
Autores principales: | Park, JinSeok, Kim, Deok-Ho, Kim, Hong-Nam, Wang, Chiaochun Joanne, Kwak, Moon Kyu, Hur, Eunmi, Suh, Kahp-Yang, An, Steven S., Levchenko, Andre |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517090/ https://www.ncbi.nlm.nih.gov/pubmed/26974411 http://dx.doi.org/10.1038/nmat4586 |
Ejemplares similares
-
Biomechanical interplay between anisotropic re-organization of cells and the surrounding matrix underlies transition to invasive cancer spread
por: Kim, Deok-Ho, et al.
Publicado: (2018) -
Designing nanotopographical density of extracellular matrix for controlled morphology and function of human mesenchymal stem cells
por: Kim, Jangho, et al.
Publicado: (2013) -
Switch-like enhancement of epithelial-mesenchymal transition by YAP through feedback regulation of WT1 and Rho-family GTPases
por: Park, JinSeok, et al.
Publicado: (2019) -
A mathematical model coupling polarity signaling to cell adhesion explains diverse cell migration patterns
por: Holmes, William R., et al.
Publicado: (2017) -
Two Distinct Filopodia Populations at the Growth Cone Allow to Sense Nanotopographical Extracellular Matrix Cues to Guide Neurite Outgrowth
por: Jang, Kyung-Jin, et al.
Publicado: (2010)