Cargando…

Pediatric Mycoplasma pneumoniae Infection Presenting with Acute Cholestatic Hepatitis and Other Extrapulmonary Manifestations in the Absence of Pneumonia

Mycoplasma pneumoniae infections mainly involve respiratory tract; however, also can manifestate other symptoms by site involved. Extrapulmonary manifestations of M. pneumoniae infection are rarely known to occur without pneumonia. Herein we report a case of a 9-year-old boy who presented with acute...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Won Jae, Kang, Ben, Lee, Hwa Pyung, Cho, Joongbum, Lee, Hae Jeong, Choe, Yon Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517379/
https://www.ncbi.nlm.nih.gov/pubmed/28730137
http://dx.doi.org/10.5223/pghn.2017.20.2.124
_version_ 1783251270248693760
author Song, Won Jae
Kang, Ben
Lee, Hwa Pyung
Cho, Joongbum
Lee, Hae Jeong
Choe, Yon Ho
author_facet Song, Won Jae
Kang, Ben
Lee, Hwa Pyung
Cho, Joongbum
Lee, Hae Jeong
Choe, Yon Ho
author_sort Song, Won Jae
collection PubMed
description Mycoplasma pneumoniae infections mainly involve respiratory tract; however, also can manifestate other symptoms by site involved. Extrapulmonary manifestations of M. pneumoniae infection are rarely known to occur without pneumonia. Herein we report a case of a 9-year-old boy who presented with acute cholestatic hepatitis in the absence of pneumonia. Rhabdomyolysis, skin rash, and initial laboratory results suspicious of disseminated intravascular coagulopathy were also observed in this patient. M. pneumoniae infection was identified by a 4-fold increase in immunoglobulin G antibodies to M. pneumoniae between acute and convalescent sera by enzyme-linked immunosorbent assay. This is the first pediatric case in Korea of M. pneumoniae infection presenting with acute cholestatic hepatitis in the absence of pneumonia.
format Online
Article
Text
id pubmed-5517379
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition
record_format MEDLINE/PubMed
spelling pubmed-55173792017-07-20 Pediatric Mycoplasma pneumoniae Infection Presenting with Acute Cholestatic Hepatitis and Other Extrapulmonary Manifestations in the Absence of Pneumonia Song, Won Jae Kang, Ben Lee, Hwa Pyung Cho, Joongbum Lee, Hae Jeong Choe, Yon Ho Pediatr Gastroenterol Hepatol Nutr Case Report Mycoplasma pneumoniae infections mainly involve respiratory tract; however, also can manifestate other symptoms by site involved. Extrapulmonary manifestations of M. pneumoniae infection are rarely known to occur without pneumonia. Herein we report a case of a 9-year-old boy who presented with acute cholestatic hepatitis in the absence of pneumonia. Rhabdomyolysis, skin rash, and initial laboratory results suspicious of disseminated intravascular coagulopathy were also observed in this patient. M. pneumoniae infection was identified by a 4-fold increase in immunoglobulin G antibodies to M. pneumoniae between acute and convalescent sera by enzyme-linked immunosorbent assay. This is the first pediatric case in Korea of M. pneumoniae infection presenting with acute cholestatic hepatitis in the absence of pneumonia. The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition 2017-06 2017-06-28 /pmc/articles/PMC5517379/ /pubmed/28730137 http://dx.doi.org/10.5223/pghn.2017.20.2.124 Text en Copyright © 2017 by The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Song, Won Jae
Kang, Ben
Lee, Hwa Pyung
Cho, Joongbum
Lee, Hae Jeong
Choe, Yon Ho
Pediatric Mycoplasma pneumoniae Infection Presenting with Acute Cholestatic Hepatitis and Other Extrapulmonary Manifestations in the Absence of Pneumonia
title Pediatric Mycoplasma pneumoniae Infection Presenting with Acute Cholestatic Hepatitis and Other Extrapulmonary Manifestations in the Absence of Pneumonia
title_full Pediatric Mycoplasma pneumoniae Infection Presenting with Acute Cholestatic Hepatitis and Other Extrapulmonary Manifestations in the Absence of Pneumonia
title_fullStr Pediatric Mycoplasma pneumoniae Infection Presenting with Acute Cholestatic Hepatitis and Other Extrapulmonary Manifestations in the Absence of Pneumonia
title_full_unstemmed Pediatric Mycoplasma pneumoniae Infection Presenting with Acute Cholestatic Hepatitis and Other Extrapulmonary Manifestations in the Absence of Pneumonia
title_short Pediatric Mycoplasma pneumoniae Infection Presenting with Acute Cholestatic Hepatitis and Other Extrapulmonary Manifestations in the Absence of Pneumonia
title_sort pediatric mycoplasma pneumoniae infection presenting with acute cholestatic hepatitis and other extrapulmonary manifestations in the absence of pneumonia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517379/
https://www.ncbi.nlm.nih.gov/pubmed/28730137
http://dx.doi.org/10.5223/pghn.2017.20.2.124
work_keys_str_mv AT songwonjae pediatricmycoplasmapneumoniaeinfectionpresentingwithacutecholestatichepatitisandotherextrapulmonarymanifestationsintheabsenceofpneumonia
AT kangben pediatricmycoplasmapneumoniaeinfectionpresentingwithacutecholestatichepatitisandotherextrapulmonarymanifestationsintheabsenceofpneumonia
AT leehwapyung pediatricmycoplasmapneumoniaeinfectionpresentingwithacutecholestatichepatitisandotherextrapulmonarymanifestationsintheabsenceofpneumonia
AT chojoongbum pediatricmycoplasmapneumoniaeinfectionpresentingwithacutecholestatichepatitisandotherextrapulmonarymanifestationsintheabsenceofpneumonia
AT leehaejeong pediatricmycoplasmapneumoniaeinfectionpresentingwithacutecholestatichepatitisandotherextrapulmonarymanifestationsintheabsenceofpneumonia
AT choeyonho pediatricmycoplasmapneumoniaeinfectionpresentingwithacutecholestatichepatitisandotherextrapulmonarymanifestationsintheabsenceofpneumonia