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Interleukin-36β provides protection against HSV-1 infection, but does not modulate initiation of adaptive immune responses
Interleukin-36 (IL-36) represents three cytokines, IL-36α, IL-36β and IL-36γ, which bind to the same receptor, IL-1RL2; however, their physiological function(s) remain poorly understood. Here, the role of IL-36 in immunity against HSV-1 was examined using the flank skin infection mouse model. Expres...
Autores principales: | Milora, Katelynn A., Uppalapati, Siva R., Sanmiguel, Julio C., Zou, Wei, Jensen, Liselotte E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517484/ https://www.ncbi.nlm.nih.gov/pubmed/28724920 http://dx.doi.org/10.1038/s41598-017-05363-4 |
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