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Transgenic Chickens Expressing the 3D8 Single Chain Variable Fragment Protein Suppress Avian Influenza Transmission
The 3D8 single chain variable fragment (scFv) is a mini-antibody that causes unusual sequence-independent nuclease activity against all types of nucleic acids. We used recombinant lentiviruses to generate transgenic chickens expressing the 3D8 scFv gene under the control of the chicken β-actin promo...
Autores principales: | June Byun, Sung, Yuk, Seong-su, Jang, Ye-Jin, Choi, Hoonsung, Jeon, Mi-Hyang, Erdene-Ochir, TO, Kwon, Jung-Hoon, Noh, Jin-Yong, Sun Kim, Jeom, Gyu YOO, Jae, Song, Chang-Seon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517518/ https://www.ncbi.nlm.nih.gov/pubmed/28724948 http://dx.doi.org/10.1038/s41598-017-05270-8 |
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