Modulation of RNA primer formation by Mn(II)-substituted T7 DNA primase

Lagging strand DNA synthesis by DNA polymerase requires RNA primers produced by DNA primase. The N-terminal primase domain of the gene 4 protein of phage T7 comprises a zinc-binding domain that recognizes a specific DNA sequence and an RNA polymerase domain that catalyzes RNA polymerization. Based o...

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Detalles Bibliográficos
Autores principales: Ilic, Stefan, Akabayov, Sabine R., Froimovici, Roy, Meiry, Ron, Vilenchik, Dan, Hernandez, Alfredo, Arthanari, Haribabu, Akabayov, Barak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517523/
https://www.ncbi.nlm.nih.gov/pubmed/28724886
http://dx.doi.org/10.1038/s41598-017-05534-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517523/
https://www.ncbi.nlm.nih.gov/pubmed/28724886
http://dx.doi.org/10.1038/s41598-017-05534-3

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