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Intraoperative optical coherence tomography in descemet stripping automated endothelial keratoplasty: pilot experiences
PURPOSE: To assess the added value of intraoperative optical coherence tomography (iOCT) in evaluating graft adhesion and graft interface in patients undergoing descemet’s stripping automated endothelial keratoplasty (DSAEK). METHODS: This is a prospective single-center case series comprising 8 eyes...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517607/ https://www.ncbi.nlm.nih.gov/pubmed/27655298 http://dx.doi.org/10.1007/s10792-016-0338-9 |
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author | Steverink, Jasper G. Wisse, Robert P. L. |
author_facet | Steverink, Jasper G. Wisse, Robert P. L. |
author_sort | Steverink, Jasper G. |
collection | PubMed |
description | PURPOSE: To assess the added value of intraoperative optical coherence tomography (iOCT) in evaluating graft adhesion and graft interface in patients undergoing descemet’s stripping automated endothelial keratoplasty (DSAEK). METHODS: This is a prospective single-center case series comprising 8 eyes of 8 patients consecutively scheduled for DSAEK surgery. iOCT imaging was performed after insertion of the graft, after pressurizing the eye, and at the end of surgery (three images per surgery). At each stage of surgery, corneal thickness and the widest gap between the recipient and the graft (i.e., maximal interface width) were measured using an image processing tool. Follow-up measurements were taken at 1 day, 3 and 6 months, post-operatively. RESULTS: Imaging was performed in 21 of 24 scheduled imaging intervals, and required little to no additional surgical time. At the end of surgery, iOCT showed persisting interfaces in six cases. One case showed a full graft detachment necessitating surgical intervention. CONCLUSION: Real-time iOCT is a safe, efficient, and useful tool in assessing graft adherence in DSAEK surgery. With adequate analysis software, iOCT has the potential to be a paradigm-shifting development in posterior lamellar surgery and could aid the clinician in further lowering the rates of graft dislocation after DSAEK. |
format | Online Article Text |
id | pubmed-5517607 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Springer Netherlands |
record_format | MEDLINE/PubMed |
spelling | pubmed-55176072017-08-03 Intraoperative optical coherence tomography in descemet stripping automated endothelial keratoplasty: pilot experiences Steverink, Jasper G. Wisse, Robert P. L. Int Ophthalmol Original Paper PURPOSE: To assess the added value of intraoperative optical coherence tomography (iOCT) in evaluating graft adhesion and graft interface in patients undergoing descemet’s stripping automated endothelial keratoplasty (DSAEK). METHODS: This is a prospective single-center case series comprising 8 eyes of 8 patients consecutively scheduled for DSAEK surgery. iOCT imaging was performed after insertion of the graft, after pressurizing the eye, and at the end of surgery (three images per surgery). At each stage of surgery, corneal thickness and the widest gap between the recipient and the graft (i.e., maximal interface width) were measured using an image processing tool. Follow-up measurements were taken at 1 day, 3 and 6 months, post-operatively. RESULTS: Imaging was performed in 21 of 24 scheduled imaging intervals, and required little to no additional surgical time. At the end of surgery, iOCT showed persisting interfaces in six cases. One case showed a full graft detachment necessitating surgical intervention. CONCLUSION: Real-time iOCT is a safe, efficient, and useful tool in assessing graft adherence in DSAEK surgery. With adequate analysis software, iOCT has the potential to be a paradigm-shifting development in posterior lamellar surgery and could aid the clinician in further lowering the rates of graft dislocation after DSAEK. Springer Netherlands 2016-09-21 2017 /pmc/articles/PMC5517607/ /pubmed/27655298 http://dx.doi.org/10.1007/s10792-016-0338-9 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Original Paper Steverink, Jasper G. Wisse, Robert P. L. Intraoperative optical coherence tomography in descemet stripping automated endothelial keratoplasty: pilot experiences |
title | Intraoperative optical coherence tomography in descemet stripping automated endothelial keratoplasty: pilot experiences |
title_full | Intraoperative optical coherence tomography in descemet stripping automated endothelial keratoplasty: pilot experiences |
title_fullStr | Intraoperative optical coherence tomography in descemet stripping automated endothelial keratoplasty: pilot experiences |
title_full_unstemmed | Intraoperative optical coherence tomography in descemet stripping automated endothelial keratoplasty: pilot experiences |
title_short | Intraoperative optical coherence tomography in descemet stripping automated endothelial keratoplasty: pilot experiences |
title_sort | intraoperative optical coherence tomography in descemet stripping automated endothelial keratoplasty: pilot experiences |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517607/ https://www.ncbi.nlm.nih.gov/pubmed/27655298 http://dx.doi.org/10.1007/s10792-016-0338-9 |
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