Gene expression reversal toward pre-adult levels in the aging human brain and age-related loss of cellular identity

It was previously reported that mRNA expression levels in the prefrontal cortex at old age start to resemble pre-adult levels. Such expression reversals could imply loss of cellular identity in the aging brain, and provide a link between aging-related molecular changes and functional decline. Here w...

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Detalles Bibliográficos
Autores principales: Dönertaş, Handan Melike, İzgi, Hamit, Kamacıoğlu, Altuğ, He, Zhisong, Khaitovich, Philipp, Somel, Mehmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517654/
https://www.ncbi.nlm.nih.gov/pubmed/28724976
http://dx.doi.org/10.1038/s41598-017-05927-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517654/
https://www.ncbi.nlm.nih.gov/pubmed/28724976
http://dx.doi.org/10.1038/s41598-017-05927-4

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