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Gene expression reversal toward pre-adult levels in the aging human brain and age-related loss of cellular identity
It was previously reported that mRNA expression levels in the prefrontal cortex at old age start to resemble pre-adult levels. Such expression reversals could imply loss of cellular identity in the aging brain, and provide a link between aging-related molecular changes and functional decline. Here w...
Autores principales: | Dönertaş, Handan Melike, İzgi, Hamit, Kamacıoğlu, Altuğ, He, Zhisong, Khaitovich, Philipp, Somel, Mehmet |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517654/ https://www.ncbi.nlm.nih.gov/pubmed/28724976 http://dx.doi.org/10.1038/s41598-017-05927-4 |
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