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Current status of pediatric transplantation in Japan
Brain-dead donor organ transplantation has been available to children in Japan since the 2010 revision of the Organ Transplant Law. Of the 50–60 brain-dead donor organ transplants performed annually in Japan, however, very few (0–4 per year) are performed in children. Again, while those receiving li...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518126/ https://www.ncbi.nlm.nih.gov/pubmed/28729907 http://dx.doi.org/10.1186/s40560-017-0241-0 |
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author | Nishimura, Nao Kasahara, Mureo Ishikura, Kenji Nakagawa, Satoshi |
author_facet | Nishimura, Nao Kasahara, Mureo Ishikura, Kenji Nakagawa, Satoshi |
author_sort | Nishimura, Nao |
collection | PubMed |
description | Brain-dead donor organ transplantation has been available to children in Japan since the 2010 revision of the Organ Transplant Law. Of the 50–60 brain-dead donor organ transplants performed annually in Japan, however, very few (0–4 per year) are performed in children. Again, while those receiving liver, heart, and kidney transplants are reported to fare better than their counterparts in the rest of the world, organ shortage is becoming a matter of great concern. Very few organs become available from brain-dead donors or are transplanted to adults if made available at all, with some children dying while on the brain-dead organ waiting list. Against this background, living-donor transplants, split-liver transplants, domino transplants, and hepatocyte transplants represent alternative modalities, each of which is shown to be associated with favorable outcomes. Challenges exist, include streamlining the existing framework for promoting organ donation for children and between children. |
format | Online Article Text |
id | pubmed-5518126 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-55181262017-07-20 Current status of pediatric transplantation in Japan Nishimura, Nao Kasahara, Mureo Ishikura, Kenji Nakagawa, Satoshi J Intensive Care Review Brain-dead donor organ transplantation has been available to children in Japan since the 2010 revision of the Organ Transplant Law. Of the 50–60 brain-dead donor organ transplants performed annually in Japan, however, very few (0–4 per year) are performed in children. Again, while those receiving liver, heart, and kidney transplants are reported to fare better than their counterparts in the rest of the world, organ shortage is becoming a matter of great concern. Very few organs become available from brain-dead donors or are transplanted to adults if made available at all, with some children dying while on the brain-dead organ waiting list. Against this background, living-donor transplants, split-liver transplants, domino transplants, and hepatocyte transplants represent alternative modalities, each of which is shown to be associated with favorable outcomes. Challenges exist, include streamlining the existing framework for promoting organ donation for children and between children. BioMed Central 2017-07-20 /pmc/articles/PMC5518126/ /pubmed/28729907 http://dx.doi.org/10.1186/s40560-017-0241-0 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Review Nishimura, Nao Kasahara, Mureo Ishikura, Kenji Nakagawa, Satoshi Current status of pediatric transplantation in Japan |
title | Current status of pediatric transplantation in Japan |
title_full | Current status of pediatric transplantation in Japan |
title_fullStr | Current status of pediatric transplantation in Japan |
title_full_unstemmed | Current status of pediatric transplantation in Japan |
title_short | Current status of pediatric transplantation in Japan |
title_sort | current status of pediatric transplantation in japan |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518126/ https://www.ncbi.nlm.nih.gov/pubmed/28729907 http://dx.doi.org/10.1186/s40560-017-0241-0 |
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