Hybrid assembly with long and short reads improves discovery of gene family expansions

BACKGROUND: Long-read and short-read sequencing technologies offer competing advantages for eukaryotic genome sequencing projects. Combinations of both may be appropriate for surveys of within-species genomic variation. METHODS: We developed a hybrid assembly pipeline called “Alpaca” that can operat...

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Detalles Bibliográficos
Autores principales: Miller, Jason R., Zhou, Peng, Mudge, Joann, Gurtowski, James, Lee, Hayan, Ramaraj, Thiruvarangan, Walenz, Brian P., Liu, Junqi, Stupar, Robert M., Denny, Roxanne, Song, Li, Singh, Namrata, Maron, Lyza G., McCouch, Susan R., McCombie, W. Richard, Schatz, Michael C., Tiffin, Peter, Young, Nevin D., Silverstein, Kevin A. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518131/
https://www.ncbi.nlm.nih.gov/pubmed/28724409
http://dx.doi.org/10.1186/s12864-017-3927-8

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