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Horse Liver Alcohol Dehydrogenase: Zinc Coordination and Catalysis
[Image: see text] During catalysis by liver alcohol dehydrogenase (ADH), a water bound to the catalytic zinc is replaced by the oxygen of the substrates. The mechanism might involve a pentacoordinated zinc or a double-displacement reaction with participation by a nearby glutamate residue, as suggest...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518280/ https://www.ncbi.nlm.nih.gov/pubmed/28640600 http://dx.doi.org/10.1021/acs.biochem.7b00446 |