Cargando…

SUMO‐modified insulin‐like growth factor 1 receptor (IGF‐1R) increases cell cycle progression and cell proliferation

Increasing number of studies have shown nuclear localization of the insulin‐like growth factor 1 receptor (nIGF‐1R) in tumor cells and its links to adverse clinical outcome in various cancers. Any obvious cell physiological roles of nIGF‐1R have, however, still not been disclosed. Previously, we rep...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Yingbo, Liu, Hongyu, Waraky, Ahmed, Haglund, Felix, Agarwal, Prasoon, Jernberg‐Wiklund, Helena, Warsito, Dudi, Larsson, Olle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518303/ https://www.ncbi.nlm.nih.gov/pubmed/28112398 http://dx.doi.org/10.1002/jcp.25818

Ejemplares similares

Nuclearly translocated insulin-like growth factor 1 receptor phosphorylates histone H3 at tyrosine 41 and induces SNAI2 expression via Brg1 chromatin remodeling protein
por: Warsito, Dudi, et al.
Publicado: (2016)

Nuclear IGF1R interact with PCNA to preserve DNA replication after DNA-damage in a variety of human cancers
por: Yang, Chen, et al.
Publicado: (2020)

Targeting the IGF-1R signaling and mechanisms for epigenetic gene silencing in human multiple myeloma
por: Jernberg-Wiklund, Helena, et al.
Publicado: (2012)

Growth signals employ CGGBP1 to suppress transcription of Alu-SINEs
por: Agarwal, Prasoon, et al.
Publicado: (2014)

CGGBP1 mitigates cytosine methylation at repetitive DNA sequences
por: Agarwal, Prasoon, et al.
Publicado: (2015)

Transcriptome profiling of Ewing sarcomas – treatment resistance pathways and IGF‐dependency
por: Chen, Yi, et al.
Publicado: (2020)

Mps1 is SUMO-modified during the cell cycle
por: Restuccia, Agnese, et al.
Publicado: (2015)

The IGF-1 receptor inhibitor picropodophyllin potentiates the anti-myeloma activity of a BH3-mimetic
por: Bieghs, Liesbeth, et al.
Publicado: (2014)

Nuclear IGF1R interacts with NuMA and regulates 53BP1-dependent DNA double-strand break repair in colorectal cancer
por: Yang, Chen, et al.
Publicado: (2021)

Picropodophyllin causes mitotic arrest and catastrophe by depolymerizing microtubules via Insulin-like growth factor-1 receptor-independent mechanism
por: Waraky, Ahmed, et al.
Publicado: (2014)

IGF-1R: SUMO-ing its weight in chemoresistant colorectal cancer
por: Goel, Ajay
Publicado: (2017)

Embryonic Cells Redistribute SUMO1 upon Forced SUMO1 Overexpression
por: Lee, Andreia, et al.
Publicado: (2019)

Role of Ubiquitination in IGF-1 Receptor Signaling and Degradation
por: Sehat, Bita, et al.
Publicado: (2007)

Increased resistance to proteasome inhibitors in multiple myeloma mediated by cIAP2 - implications for a combinatorial treatment
por: Duvefelt, Charlotte Fristedt, et al.
Publicado: (2015)

SUMO1 modification stabilizes CDK6 protein and drives the cell cycle and glioblastoma progression
por: Bellail, Anita C., et al.
Publicado: (2014)

Sumo-dependent substrate targeting of the SUMO protease Ulp1
por: Elmore, Zachary C, et al.
Publicado: (2011)

SUMO1 modification of IGF-1R combining with SNAI2 inhibited osteogenic differentiation of PDLSCs stimulated by high glucose
por: Jiang, Rongrong, et al.
Publicado: (2021)

Molecular Characterization of Acquired Tolerance of Tumor Cells to Picropodophyllin (PPP)
por: Hashemi, Jamileh, et al.
Publicado: (2011)

A Fasting Insulin–Raising Allele at IGF1 Locus Is Associated with Circulating Levels of IGF-1 and Insulin Sensitivity
por: Mannino, Gaia Chiara, et al.
Publicado: (2013)

Differential effects of SUMO1 and SUMO3 on PKR activation and stability
por: Maarifi, Ghizlane, et al.
Publicado: (2018)

SUMO targeting of a stress-tolerant Ulp1 SUMO protease
por: Peek, Jennifer, et al.
Publicado: (2018)

Cell Cycle–Regulated Attachment of the Ubiquitin-Related Protein Sumo to the Yeast Septins
por: Johnson, Erica S., et al.
Publicado: (1999)

The miR-125a and miR-320c are potential tumor suppressor microRNAs epigenetically silenced by the polycomb repressive complex 2 in multiple myeloma
por: Alzrigat, Mohammad, et al.
Publicado: (2017)

Meta-analysis of SUMO1
por: Wilson, Brian J
Publicado: (2008)

EZH2 inhibition in multiple myeloma downregulates myeloma associated oncogenes and upregulates microRNAs with potential tumor suppressor functions
por: Alzrigat, Mohammad, et al.
Publicado: (2016)

The Sumo proteome of proliferating and neuronal-differentiating cells reveals Utf1 among key Sumo targets involved in neurogenesis
por: Correa-Vázquez, Juan F., et al.
Publicado: (2021)

Epstein-Barr Virus Latent Membrane Protein-1 Induces the Expression of SUMO-1 and SUMO-2/3 in LMP1-positive Lymphomas and Cells
por: Salahuddin, Sadia, et al.
Publicado: (2019)

Specific insulin/IGF1 hybrid receptor activation assay reveals IGF1 as a more potent ligand than insulin
por: Slaaby, Rita
Publicado: (2015)

Central insulin‐like growth factor‐1 (IGF‐1) restores whole‐body insulin action in a model of age‐related insulin resistance and IGF‐1 decline
por: Huffman, Derek M., et al.
Publicado: (2015)

IGF1 and IGF2 specificities to the two insulin receptor isoforms are determined by insulin receptor amino acid 718
por: Andersen, Mie, et al.
Publicado: (2017)

Polycomb Target Genes Are Silenced in Multiple Myeloma
por: Kalushkova, Antonia, et al.
Publicado: (2010)

Sensitization and translocation of TRPV1 by insulin and IGF-I
por: Van Buren, Jeremy J, et al.
Publicado: (2005)

Associations among IGF-1, IGF2, IGF-1R, IGF-2R, IGFBP-3, insulin genetic polymorphisms and central precocious puberty in girls
por: Chang, Hua-Pin, et al.
Publicado: (2018)

Insulin mediates de novo nuclear accumulation of the IGF-1/insulin Hybrid Receptor in corneal epithelial cells
por: Titone, Rossella, et al.
Publicado: (2018)

Analysis of SUMO1-conjugation at synapses
por: Daniel, James A, et al.
Publicado: (2017)

Effects of human insulin and insulin aspart preparations on levels of IGF-I, IGFBPs and IGF bioactivity in patients with type 1 diabetes
por: Ma, Zhulin, et al.
Publicado: (2014)

Expression of SUMO1P3 Compared with SUMO1 is an Independent Predictor of Patient Outcome in Lung Adenocarcinoma
por: Su, Xiaolan, et al.
Publicado: (2019)

Insulin growth factor 1 like receptor (IGF-1R)
por: Iyer, Gopal, et al.
Publicado: (2016)

Phase separation of insulin receptor substrate 1 drives the formation of insulin/IGF-1 signalosomes
por: Gao, Xiu Kui, et al.
Publicado: (2022)

Dynamic SUMO modification regulates mitotic chromosome assembly and cell cycle progression in Caenorhabditis elegans
por: Pelisch, Federico, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_79p2j7ee1c835drg9pa6ut95lj