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Extraordinary radiation super-sensitivity accompanying with sorafenib combination therapy: what lies beneath?

Primary liver tumor, especially hepatocellular carcinoma (HCC), is a common cause of cancer death worldwide. The incidence is generally higher in Asian countries than in western countries. Carcinogenesis of HCC is often associated with hepatitis viral infections. Current standard treatment of HCC is...

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Autores principales: Lee, Jayoung, Lee, Ju Hye, Yoon, Hanbin, Lee, Ho Jeong, Jeon, Hosang, Nam, Jiho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Radiation Oncology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518458/
https://www.ncbi.nlm.nih.gov/pubmed/28712281
http://dx.doi.org/10.3857/roj.2017.00262
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author Lee, Jayoung
Lee, Ju Hye
Yoon, Hanbin
Lee, Ho Jeong
Jeon, Hosang
Nam, Jiho
author_facet Lee, Jayoung
Lee, Ju Hye
Yoon, Hanbin
Lee, Ho Jeong
Jeon, Hosang
Nam, Jiho
author_sort Lee, Jayoung
collection PubMed
description Primary liver tumor, especially hepatocellular carcinoma (HCC), is a common cause of cancer death worldwide. The incidence is generally higher in Asian countries than in western countries. Carcinogenesis of HCC is often associated with hepatitis viral infections. Current standard treatment of HCC is surgical resection or transplantation in patients with early stage disease. However, the patient with advanced stage disease, surgical resection is often limited. Sorafenib or other treatment modalities are not so effective as well. We report a case of unusual radiation super-sensitivity in advanced stage HCC, and review the literature.
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spelling pubmed-55184582017-07-20 Extraordinary radiation super-sensitivity accompanying with sorafenib combination therapy: what lies beneath? Lee, Jayoung Lee, Ju Hye Yoon, Hanbin Lee, Ho Jeong Jeon, Hosang Nam, Jiho Radiat Oncol J Case Report Primary liver tumor, especially hepatocellular carcinoma (HCC), is a common cause of cancer death worldwide. The incidence is generally higher in Asian countries than in western countries. Carcinogenesis of HCC is often associated with hepatitis viral infections. Current standard treatment of HCC is surgical resection or transplantation in patients with early stage disease. However, the patient with advanced stage disease, surgical resection is often limited. Sorafenib or other treatment modalities are not so effective as well. We report a case of unusual radiation super-sensitivity in advanced stage HCC, and review the literature. The Korean Society for Radiation Oncology 2017-06 2017-06-30 /pmc/articles/PMC5518458/ /pubmed/28712281 http://dx.doi.org/10.3857/roj.2017.00262 Text en Copyright © 2017. The Korean Society for Radiation Oncology This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (http://creativecommons.org/licenses/by-nc/4.0) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Lee, Jayoung
Lee, Ju Hye
Yoon, Hanbin
Lee, Ho Jeong
Jeon, Hosang
Nam, Jiho
Extraordinary radiation super-sensitivity accompanying with sorafenib combination therapy: what lies beneath?
title Extraordinary radiation super-sensitivity accompanying with sorafenib combination therapy: what lies beneath?
title_full Extraordinary radiation super-sensitivity accompanying with sorafenib combination therapy: what lies beneath?
title_fullStr Extraordinary radiation super-sensitivity accompanying with sorafenib combination therapy: what lies beneath?
title_full_unstemmed Extraordinary radiation super-sensitivity accompanying with sorafenib combination therapy: what lies beneath?
title_short Extraordinary radiation super-sensitivity accompanying with sorafenib combination therapy: what lies beneath?
title_sort extraordinary radiation super-sensitivity accompanying with sorafenib combination therapy: what lies beneath?
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518458/
https://www.ncbi.nlm.nih.gov/pubmed/28712281
http://dx.doi.org/10.3857/roj.2017.00262
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