Resurgence of Polymyxin B for MDR/XDR Gram-Negative Infections: An Overview of Current Evidence

Polymyxin B has resurged in recent years as a last resort therapy for Gram-negative multidrug-resistant (MDR) and extremely drug resistant (XDR) infections. Understanding newer evidence on polymyxin B is necessary to guide clinical decision making. Here, we present a literature review of polymyxin B...

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Autores principales: Garg, Suneel Kumar, Singh, Omender, Juneja, Deven, Tyagi, Niraj, Khurana, Amandeep Singh, Qamra, Amit, Motlekar, Salman, Barkate, Hanmant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518490/
https://www.ncbi.nlm.nih.gov/pubmed/28761764
http://dx.doi.org/10.1155/2017/3635609
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author Garg, Suneel Kumar
Singh, Omender
Juneja, Deven
Tyagi, Niraj
Khurana, Amandeep Singh
Qamra, Amit
Motlekar, Salman
Barkate, Hanmant
author_facet Garg, Suneel Kumar
Singh, Omender
Juneja, Deven
Tyagi, Niraj
Khurana, Amandeep Singh
Qamra, Amit
Motlekar, Salman
Barkate, Hanmant
author_sort Garg, Suneel Kumar
collection PubMed
description Polymyxin B has resurged in recent years as a last resort therapy for Gram-negative multidrug-resistant (MDR) and extremely drug resistant (XDR) infections. Understanding newer evidence on polymyxin B is necessary to guide clinical decision making. Here, we present a literature review of polymyxin B in Gram-negative infections with update on its pharmacology.
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spelling pubmed-55184902017-07-31 Resurgence of Polymyxin B for MDR/XDR Gram-Negative Infections: An Overview of Current Evidence Garg, Suneel Kumar Singh, Omender Juneja, Deven Tyagi, Niraj Khurana, Amandeep Singh Qamra, Amit Motlekar, Salman Barkate, Hanmant Crit Care Res Pract Review Article Polymyxin B has resurged in recent years as a last resort therapy for Gram-negative multidrug-resistant (MDR) and extremely drug resistant (XDR) infections. Understanding newer evidence on polymyxin B is necessary to guide clinical decision making. Here, we present a literature review of polymyxin B in Gram-negative infections with update on its pharmacology. Hindawi 2017 2017-07-06 /pmc/articles/PMC5518490/ /pubmed/28761764 http://dx.doi.org/10.1155/2017/3635609 Text en Copyright © 2017 Suneel Kumar Garg et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Garg, Suneel Kumar
Singh, Omender
Juneja, Deven
Tyagi, Niraj
Khurana, Amandeep Singh
Qamra, Amit
Motlekar, Salman
Barkate, Hanmant
Resurgence of Polymyxin B for MDR/XDR Gram-Negative Infections: An Overview of Current Evidence
title Resurgence of Polymyxin B for MDR/XDR Gram-Negative Infections: An Overview of Current Evidence
title_full Resurgence of Polymyxin B for MDR/XDR Gram-Negative Infections: An Overview of Current Evidence
title_fullStr Resurgence of Polymyxin B for MDR/XDR Gram-Negative Infections: An Overview of Current Evidence
title_full_unstemmed Resurgence of Polymyxin B for MDR/XDR Gram-Negative Infections: An Overview of Current Evidence
title_short Resurgence of Polymyxin B for MDR/XDR Gram-Negative Infections: An Overview of Current Evidence
title_sort resurgence of polymyxin b for mdr/xdr gram-negative infections: an overview of current evidence
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518490/
https://www.ncbi.nlm.nih.gov/pubmed/28761764
http://dx.doi.org/10.1155/2017/3635609
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