Rapamycin alleviates inflammation and muscle weakness, while altering the Treg/Th17 balance in a rat model of myasthenia gravis

Myasthenia gravis (MG) is an autoimmune disease commonly treated with immunosuppressants. We evaluated the novel immunosuppressant, rapamycin (RAPA), in a rat model of experimental autoimmune MG (EAMG). Mortality rates in the RAPA (12%) were significantly down compared with the EAMG (88%) or cycloph...

Descripción completa

Detalles Bibliográficos
Autores principales: Jing, Feng, Yang, Fei, Cui, Fang, Chen, Zhaohui, Ling, Li, Huang, Xusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518538/
https://www.ncbi.nlm.nih.gov/pubmed/28655853
http://dx.doi.org/10.1042/BSR20170767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518538/
https://www.ncbi.nlm.nih.gov/pubmed/28655853
http://dx.doi.org/10.1042/BSR20170767

Ejemplares similares