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Sigmar1 regulates endoplasmic reticulum stress-induced C/EBP-homologous protein expression in cardiomyocytes

C/EBP-homologous protein (CHOP) is a ubiquitously expressed stress-inducible transcription factor robustly induced by maladaptive endoplasmic reticulum (ER) stresses in a wide variety of cells. Here, we examined a novel function of Sigma 1 receptor (Sigmar1) in regulating CHOP expression under ER st...

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Detalles Bibliográficos
Autores principales: Alam, Shafiul, Abdullah, Chowdhury S., Aishwarya, Richa, Orr, A. Wayne, Traylor, James, Miriyala, Sumitra, Panchatcharam, Manikandan, Pattillo, Christopher B., Bhuiyan, Md. Shenuarin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518542/
https://www.ncbi.nlm.nih.gov/pubmed/28667101
http://dx.doi.org/10.1042/BSR20170898