Nine compounds from the root bark of Lycium chinense and their anti-inflammatory activitieslammatory activitiesretain-->

Two new compounds, named lyciumlignan D (1) and lyciumphenyl propanoid A (2), along with seven known compounds, were isolated from the root bark of Lycium chinense. Their structures were elucidated using spectroscopic data (UV, IR, HR-ESI-MS, 1D and 2D NMR, CD), as well as by comparison with those o...

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Detalles Bibliográficos
Autores principales: Yang, Yanan, An, Yawen, Wang, Wei, Du, Ning, Zhang, Jinghua, Feng, Ziming, Jiang, Jianshuang, Zhang, Peicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518643/
https://www.ncbi.nlm.nih.gov/pubmed/28752035
http://dx.doi.org/10.1016/j.apsb.2017.04.004
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author Yang, Yanan
An, Yawen
Wang, Wei
Du, Ning
Zhang, Jinghua
Feng, Ziming
Jiang, Jianshuang
Zhang, Peicheng
author_facet Yang, Yanan
An, Yawen
Wang, Wei
Du, Ning
Zhang, Jinghua
Feng, Ziming
Jiang, Jianshuang
Zhang, Peicheng
author_sort Yang, Yanan
collection PubMed
description Two new compounds, named lyciumlignan D (1) and lyciumphenyl propanoid A (2), along with seven known compounds, were isolated from the root bark of Lycium chinense. Their structures were elucidated using spectroscopic data (UV, IR, HR-ESI-MS, 1D and 2D NMR, CD), as well as by comparison with those of the literature. Compounds 3—9 were isolated from this genus for the first time. In the in vitro assay, compounds 3, 6, and 7 exhibited stronger anti-inflammatory effects than the positive control curcumin at a concentration of 10 μmol/L.
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spelling pubmed-55186432017-07-27 Nine compounds from the root bark of Lycium chinense and their anti-inflammatory activitieslammatory activitiesretain--> Yang, Yanan An, Yawen Wang, Wei Du, Ning Zhang, Jinghua Feng, Ziming Jiang, Jianshuang Zhang, Peicheng Acta Pharm Sin B Original Article Two new compounds, named lyciumlignan D (1) and lyciumphenyl propanoid A (2), along with seven known compounds, were isolated from the root bark of Lycium chinense. Their structures were elucidated using spectroscopic data (UV, IR, HR-ESI-MS, 1D and 2D NMR, CD), as well as by comparison with those of the literature. Compounds 3—9 were isolated from this genus for the first time. In the in vitro assay, compounds 3, 6, and 7 exhibited stronger anti-inflammatory effects than the positive control curcumin at a concentration of 10 μmol/L. Elsevier 2017-07 2017-05-03 /pmc/articles/PMC5518643/ /pubmed/28752035 http://dx.doi.org/10.1016/j.apsb.2017.04.004 Text en © 2017 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Yang, Yanan
An, Yawen
Wang, Wei
Du, Ning
Zhang, Jinghua
Feng, Ziming
Jiang, Jianshuang
Zhang, Peicheng
Nine compounds from the root bark of Lycium chinense and their anti-inflammatory activitieslammatory activitiesretain-->
title Nine compounds from the root bark of Lycium chinense and their anti-inflammatory activitieslammatory activitiesretain-->
title_full Nine compounds from the root bark of Lycium chinense and their anti-inflammatory activitieslammatory activitiesretain-->
title_fullStr Nine compounds from the root bark of Lycium chinense and their anti-inflammatory activitieslammatory activitiesretain-->
title_full_unstemmed Nine compounds from the root bark of Lycium chinense and their anti-inflammatory activitieslammatory activitiesretain-->
title_short Nine compounds from the root bark of Lycium chinense and their anti-inflammatory activitieslammatory activitiesretain-->
title_sort nine compounds from the root bark of lycium chinense and their anti-inflammatory activitieslammatory activitiesretain-->
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518643/
https://www.ncbi.nlm.nih.gov/pubmed/28752035
http://dx.doi.org/10.1016/j.apsb.2017.04.004
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