Maternal obesity programs increased leptin gene expression in rat male offspring via epigenetic modifications in a depot-specific manner

OBJECTIVE: According to the Developmental Origin of Health and Disease (DOHaD) concept, maternal obesity and accelerated growth in neonates predispose offspring to white adipose tissue (WAT) accumulation. In rodents, adipogenesis mainly develops during lactation. The mechanisms underlying the phenom...

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Detalles Bibliográficos
Autores principales: Lecoutre, Simon, Oger, Frederik, Pourpe, Charlène, Butruille, Laura, Marousez, Lucie, Dickes-Coopman, Anne, Laborie, Christine, Guinez, Céline, Lesage, Jean, Vieau, Didier, Junien, Claudine, Eberlé, Delphine, Gabory, Anne, Eeckhoute, Jérôme, Breton, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518658/
https://www.ncbi.nlm.nih.gov/pubmed/28752055
http://dx.doi.org/10.1016/j.molmet.2017.05.010

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