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Biased activity of soluble guanylyl cyclase: the Janus face of thymoquinone

The natural compound thymoquinone, extracted from Nigella sativa (black cumin), is widely used in humans for its anti-oxidative properties. Thymoquinone is known for its acute endothelium-independent vasodilator effects in isolated rat aortae and pulmonary arteries, depending in part on activation o...

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Detalles Bibliográficos
Autores principales: Detremmerie, Charlotte, Vanhoutte, Paul M., Leung, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518662/
https://www.ncbi.nlm.nih.gov/pubmed/28752025
http://dx.doi.org/10.1016/j.apsb.2017.06.003