Inhibition of neurotensin receptor 1 induces intrinsic apoptosis via let-7a-3p/Bcl-w axis in glioblastoma

BACKGROUD: Glioblastoma is a kind of highly malignant and aggressive tumours in the central nervous system. Previously, we found that neurotensin (NTS) and its high-affinity receptor 1 (NTSR1) had essential roles in cell proliferation and invasiveness of glioblastoma. Unexpectedly, cell death also a...

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Detalles Bibliográficos
Autores principales: Dong, Zhen, Lei, Qian, Yang, Rui, Zhu, Shunqin, Ke, Xiao-Xue, Yang, Liqun, Cui, Hongjuan, Yi, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518855/
https://www.ncbi.nlm.nih.gov/pubmed/28494471
http://dx.doi.org/10.1038/bjc.2017.126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518855/
https://www.ncbi.nlm.nih.gov/pubmed/28494471
http://dx.doi.org/10.1038/bjc.2017.126

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