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Efficacy of anti-PD-1 therapy in patients with melanoma brain metastases

BACKGROUND: There is limited data on the efficacy of anti-programmed death 1 (PD-1) antibodies in patients (pts) with melanoma brain metastasis (BM), particularly those which are symptomatic. METHOD: We retrospectively assessed pts with melanoma BM treated with PD-1 antibodies, nivolumab and pembrol...

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Detalles Bibliográficos
Autores principales: Parakh, Sagun, Park, John J, Mendis, Shehara, Rai, Rajat, Xu, Wen, Lo, Serigne, Drummond, Martin, Rowe, Catherine, Wong, Annie, McArthur, Grant, Haydon, Andrew, Andrews, Miles C, Cebon, Jonathan, Guminski, Alex, Kefford, Richard F, Long, Georgina V, Menzies, Alexander M, Klein, Oliver, Carlino, Matteo S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518864/
https://www.ncbi.nlm.nih.gov/pubmed/28524161
http://dx.doi.org/10.1038/bjc.2017.142