Establishment of a Quick and Highly Accurate Breath Test for ALDH2 Genotyping

OBJECTIVES: Acetaldehyde, the first metabolite of ethanol, is a definite carcinogen for the esophagus, head, and neck; and aldehyde dehydrogenase 2 (ALDH2) is a mitochondrial enzyme that catalyzes the metabolism of acetaldehyde. The ALDH2 genotype exists as ALDH2*1/*1 (active ALDH2), ALDH2*1/*2 (het...

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Detalles Bibliográficos
Autores principales: Aoyama, Ikuo, Ohashi, Shinya, Amanuma, Yusuke, Hirohashi, Kenshiro, Mizumoto, Ayaka, Funakoshi, Makiko, Tsurumaki, Mihoko, Nakai, Yukie, Tanaka, Katsuyuki, Hanada, Mariko, Uesaka, Aki, Chiba, Tsutomu, Muto, Manabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518947/
https://www.ncbi.nlm.nih.gov/pubmed/28594397
http://dx.doi.org/10.1038/ctg.2017.24

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