Cargando…

Intracellular HMGB1 as a novel tumor suppressor of pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) driven by oncogenic K-Ras remains among the most lethal human cancers despite recent advances in modern medicine. The pathogenesis of PDAC is partly attributable to intrinsic chromosome instability and extrinsic inflammation activation. However, the molecular...

Descripción completa

Detalles Bibliográficos
Autores principales: Kang, Rui, Xie, Yangchun, Zhang, Qiuhong, Hou, Wen, Jiang, Qingping, Zhu, Shan, Liu, Jinbao, Zeng, Dexing, Wang, Haichao, Bartlett, David L, Billiar, Timothy R, Zeh, Herbert J, Lotze, Michael T, Tang, Daolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518983/
https://www.ncbi.nlm.nih.gov/pubmed/28374746
http://dx.doi.org/10.1038/cr.2017.51