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Upregulation of mitochondrial NAD(+) levels impairs the clonogenicity of SSEA1(+) glioblastoma tumor-initiating cells

Emerging evidence has emphasized the importance of cancer therapies targeting an abnormal metabolic state of tumor-initiating cells (TICs) in which they retain stem cell-like phenotypes and nicotinamide adenine dinucleotide (NAD(+)) metabolism. However, the functional role of NAD(+) metabolism in re...

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Detalles Bibliográficos
Autores principales:	Son, Myung Jin, Ryu, Jae-Sung, Kim, Jae Yun, Kwon, Youjeong, Chung, Kyung-Sook, Mun, Seon Ju, Cho, Yee Sook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519015/ https://www.ncbi.nlm.nih.gov/pubmed/28604662 http://dx.doi.org/10.1038/emm.2017.74

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