Differing roles for short chain fatty acids and GPR43 agonism in the regulation of intestinal barrier function and immune responses

Inflammatory bowel disease (IBD) is associated with a loss of intestinal barrier function and dysregulated immune responses. It has been shown that short chain fatty acids (SCFAs) are protective in IBD and that GPR43 mediates the protective effects of SCFAs. In this study, we investigated the effect...

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Detalles Bibliográficos
Autores principales: D’Souza, Warren N., Douangpanya, Jason, Mu, Sharon, Jaeckel, Peter, Zhang, Ming, Maxwell, Joseph R., Rottman, James B., Labitzke, Katja, Willee, Angela, Beckmann, Holger, Wang, Yingcai, Li, Yang, Schwandner, Ralf, Johnston, James A., Towne, Jennifer E., Hsu, Hailing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519041/
https://www.ncbi.nlm.nih.gov/pubmed/28727837
http://dx.doi.org/10.1371/journal.pone.0180190

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