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Genetically engineered suicide gene in mesenchymal stem cells using a Tet-On system for anaplastic thyroid cancer
Anaplastic thyroid cancer (ATC) is the most aggressive malignancy of the thyroid, during which undifferentiated tumors arise from the thyroid follicular epithelium. ATC has a very poor prognosis due to its aggressive behavior and poor response to conventional therapies. Gene-directed enzyme/prodrug...
Autores principales: | Kalimuthu, Senthilkumar, Oh, Ji Min, Gangadaran, Prakash, Zhu, Liya, Lee, Ho Won, Jeon, Yong Hyun, Jeong, Shin Young, Lee, Sang-Woo, Lee, Jaetae, Ahn, Byeong-Cheol |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519161/ https://www.ncbi.nlm.nih.gov/pubmed/28727740 http://dx.doi.org/10.1371/journal.pone.0181318 |
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