Limited nucleotide pools restrict Epstein–Barr virus-mediated B-cell immortalization

Activation of cellular oncogenes as well as infection with tumor viruses can promote aberrant proliferation and activation of the host DNA damage response. Epstein–Barr virus (EBV) infection of primary human B cells induces a transient period of hyper-proliferation, but many of these infected cells...

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Detalles Bibliográficos
Autores principales: Hafez, A Y, Messinger, J E, McFadden, K, Fenyofalvi, G, Shepard, C N, Lenzi, G M, Kim, B, Luftig, M A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519195/
https://www.ncbi.nlm.nih.gov/pubmed/28604764
http://dx.doi.org/10.1038/oncsis.2017.46

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