A Successful Therapeutic Challenge: Local Reirradiation of Breast Cancer with a Single Dose of 18 Gy Intraoperative Radiation Therapy (IORT)

After standard treatment of primary breast cancer, local relapse can develop in a previously irradiated region. The decision to refer a patient for a second radiotherapy must be thoroughly evaluated due to the increased risk of side effects. We report a case of a 43-year-old Caucasian female with a...

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Detalles Bibliográficos
Autores principales: Bonzano, Elisabetta, Guenzi, Marina, Corvò, Renzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2017
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519315/
https://www.ncbi.nlm.nih.gov/pubmed/28744423
http://dx.doi.org/10.7759/cureus.1376
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author Bonzano, Elisabetta
Guenzi, Marina
Corvò, Renzo
author_facet Bonzano, Elisabetta
Guenzi, Marina
Corvò, Renzo
author_sort Bonzano, Elisabetta
collection PubMed
description After standard treatment of primary breast cancer, local relapse can develop in a previously irradiated region. The decision to refer a patient for a second radiotherapy must be thoroughly evaluated due to the increased risk of side effects. We report a case of a 43-year-old Caucasian female with a history of left breast lumpectomy and radiation treatment in 1990 for an invasive ductal carcinoma who presented with a locoregional recurrence 19 years later. After careful evaluation, the patient has undergone a second breast-conserving surgery and successful reirradiation with 18 Gy single dose of intraoperative radiation therapy (IORT).
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spelling pubmed-55193152017-07-25 A Successful Therapeutic Challenge: Local Reirradiation of Breast Cancer with a Single Dose of 18 Gy Intraoperative Radiation Therapy (IORT) Bonzano, Elisabetta Guenzi, Marina Corvò, Renzo Cureus Oncology After standard treatment of primary breast cancer, local relapse can develop in a previously irradiated region. The decision to refer a patient for a second radiotherapy must be thoroughly evaluated due to the increased risk of side effects. We report a case of a 43-year-old Caucasian female with a history of left breast lumpectomy and radiation treatment in 1990 for an invasive ductal carcinoma who presented with a locoregional recurrence 19 years later. After careful evaluation, the patient has undergone a second breast-conserving surgery and successful reirradiation with 18 Gy single dose of intraoperative radiation therapy (IORT). Cureus 2017-06-20 /pmc/articles/PMC5519315/ /pubmed/28744423 http://dx.doi.org/10.7759/cureus.1376 Text en Copyright © 2017, Bonzano et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Oncology
Bonzano, Elisabetta
Guenzi, Marina
Corvò, Renzo
A Successful Therapeutic Challenge: Local Reirradiation of Breast Cancer with a Single Dose of 18 Gy Intraoperative Radiation Therapy (IORT)
title A Successful Therapeutic Challenge: Local Reirradiation of Breast Cancer with a Single Dose of 18 Gy Intraoperative Radiation Therapy (IORT)
title_full A Successful Therapeutic Challenge: Local Reirradiation of Breast Cancer with a Single Dose of 18 Gy Intraoperative Radiation Therapy (IORT)
title_fullStr A Successful Therapeutic Challenge: Local Reirradiation of Breast Cancer with a Single Dose of 18 Gy Intraoperative Radiation Therapy (IORT)
title_full_unstemmed A Successful Therapeutic Challenge: Local Reirradiation of Breast Cancer with a Single Dose of 18 Gy Intraoperative Radiation Therapy (IORT)
title_short A Successful Therapeutic Challenge: Local Reirradiation of Breast Cancer with a Single Dose of 18 Gy Intraoperative Radiation Therapy (IORT)
title_sort successful therapeutic challenge: local reirradiation of breast cancer with a single dose of 18 gy intraoperative radiation therapy (iort)
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519315/
https://www.ncbi.nlm.nih.gov/pubmed/28744423
http://dx.doi.org/10.7759/cureus.1376
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