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Energetics of side-chain partitioning of β-signal residues in unassisted folding of a transmembrane β-barrel protein
The free energy of water-to-interface amino acid partitioning is a major contributing factor in membrane protein folding and stability. The interface residues at the C terminus of transmembrane β-barrels form the β-signal motif required for assisted β-barrel assembly in vivo but are believed to be l...
Autores principales: | Iyer, Bharat Ramasubramanian, Zadafiya, Punit, Vetal, Pallavi Vijay, Mahalakshmi, Radhakrishnan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519381/ https://www.ncbi.nlm.nih.gov/pubmed/28592485 http://dx.doi.org/10.1074/jbc.M117.789446 |
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