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The histone demethylase KDM3A, and its downstream target MCAM, promote Ewing Sarcoma cell migration and metastasis

Ewing Sarcoma is the second most common solid pediatric malignant neoplasm of bone and soft tissue. Driven by EWS/Ets, or rarely variant, oncogenic fusions, Ewing Sarcoma is a biologically and clinically aggressive disease with a high propensity for metastasis. However, the mechanisms underpinning E...

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Detalles Bibliográficos
Autores principales:	Sechler, Marybeth, Parrish, Janet K., Birks, Diane K., Jedlicka, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519422/ https://www.ncbi.nlm.nih.gov/pubmed/28319067 http://dx.doi.org/10.1038/onc.2017.44

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