CTCF genetic alterations in endometrial carcinoma are pro-tumorigenic

CTCF is a haploinsufficient tumour suppressor gene with diverse normal functions in genome structure and gene regulation. However the mechanism by which CTCF haploinsufficiency contributes to cancer development is not well understood. CTCF is frequently mutated in endometrial cancer. Here we show th...

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Detalles Bibliográficos
Autores principales: Marshall, A D, Bailey, C G, Champ, K, Vellozzi, M, O'Young, P, Metierre, C, Feng, Y, Thoeng, A, Richards, A M, Schmitz, U, Biro, M, Jayasinghe, R, Ding, L, Anderson, L, Mardis, E R, Rasko, J E J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519450/
https://www.ncbi.nlm.nih.gov/pubmed/28319062
http://dx.doi.org/10.1038/onc.2017.25

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