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Thrombin-Derived Host-Defense Peptides Modulate Monocyte/Macrophage Inflammatory Responses to Gram-Negative Bacteria

Host-defense peptides play a fundamental role in the innate immune system by modulating inflammatory responses. Previously, it was shown that the thrombin derived host-defense peptide GKY25 inhibits LPS-induced responses of monocytes and macrophages in vitro, ex vivo, and in vivo. In this study, the...

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Detalles Bibliográficos
Autores principales: Hansen, Finja C., Strömdahl, Ann-Charlotte, Mörgelin, Matthias, Schmidtchen, Artur, van der Plas, Mariena J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519531/
https://www.ncbi.nlm.nih.gov/pubmed/28785265
http://dx.doi.org/10.3389/fimmu.2017.00843