Cargando…

Thrombin-Derived Host-Defense Peptides Modulate Monocyte/Macrophage Inflammatory Responses to Gram-Negative Bacteria

Host-defense peptides play a fundamental role in the innate immune system by modulating inflammatory responses. Previously, it was shown that the thrombin derived host-defense peptide GKY25 inhibits LPS-induced responses of monocytes and macrophages in vitro, ex vivo, and in vivo. In this study, the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hansen, Finja C., Strömdahl, Ann-Charlotte, Mörgelin, Matthias, Schmidtchen, Artur, van der Plas, Mariena J. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519531/ https://www.ncbi.nlm.nih.gov/pubmed/28785265 http://dx.doi.org/10.3389/fimmu.2017.00843

Ejemplares similares

Differential Internalization of Thrombin-Derived Host Defense Peptides into Monocytes and Macrophages
por: Hansen, Finja C., et al.
Publicado: (2021)

Host Defense Peptides of Thrombin Modulate Inflammation and Coagulation in Endotoxin-Mediated Shock and Pseudomonas aeruginosa Sepsis
por: Kalle, Martina, et al.
Publicado: (2012)

Proteolysis of Human Thrombin Generates Novel Host Defense Peptides
por: Papareddy, Praveen, et al.
Publicado: (2010)

Pseudomonas aeruginosa elastase cleaves a C-terminal peptide from human thrombin that inhibits host inflammatory responses
por: van der Plas, Mariena J. A., et al.
Publicado: (2016)

Thrombin-derived C-terminal fragments aggregate and scavenge bacteria and their proinflammatory products
por: Petrlova, Jitka, et al.
Publicado: (2020)

Proteolytic signatures define unique thrombin-derived peptides present in human wound fluid in vivo
por: Saravanan, Rathi, et al.
Publicado: (2017)

A Peptide of Heparin Cofactor II Inhibits Endotoxin-Mediated Shock and Invasive Pseudomonas aeruginosa Infection
por: Kalle, Martina, et al.
Publicado: (2014)

The TFPI-2 Derived Peptide EDC34 Improves Outcome of Gram-Negative Sepsis
por: Papareddy, Praveen, et al.
Publicado: (2013)

Thrombin-Derived Peptides Potentiate the Activity of Gram-Positive-Specific Antibiotics against Gram-Negative Bacteria
por: Wesseling, Charlotte M. J., et al.
Publicado: (2021)

Outer Membrane Vesicles Protect Gram-Negative Bacteria against Host Defense Peptides
por: Balhuizen, Melanie D., et al.
Publicado: (2021)

Thrombin-derived host defence peptide modulates neutrophil rolling and migration in vitro and functional response in vivo
por: Lim, Chun Hwee, et al.
Publicado: (2017)

Bioinformatic Analysis of the Wound Peptidome Reveals Potential Biomarkers and Antimicrobial Peptides
por: Hartman, Erik, et al.
Publicado: (2021)

Thrombin-Derived C-Terminal Peptide Reduces Candida-Induced Inflammation and Infection In Vitro and In Vivo
por: Dahlman, Anna, et al.
Publicado: (2021)

Editorial: Methods and applications in inflammation pharmacology
por: Schmidtchen, Artur, et al.
Publicado: (2022)

Maggot Secretions Skew Monocyte-Macrophage Differentiation Away from a Pro-Inflammatory to a Pro-Angiogenic Type
por: van der Plas, Mariena J. A., et al.
Publicado: (2009)

Method development and characterisation of the low-molecular-weight peptidome of human wound fluids
por: van der Plas, Mariena JA, et al.
Publicado: (2021)

Inflammation Biomarkers and Correlation to Wound Status After Full-Thickness Skin Grafting
por: Saleh, Karim, et al.
Publicado: (2019)

Concentration- and pH-Dependent Oligomerization of the Thrombin-Derived C-Terminal Peptide TCP-25
por: Petruk, Ganna, et al.
Publicado: (2020)

Cell-Free DNA Promotes Thrombin Autolysis and Generation of Thrombin-Derived C-Terminal Fragments
por: Saravanan, Rathi, et al.
Publicado: (2021)

Thrombin–Fibrin(ogen) Interactions, Host Defense and Risk of Thrombosis
por: Hulshof, Anne-Marije, et al.
Publicado: (2021)

The role of full-length apoE in clearance of Gram-negative bacteria and their endotoxins
por: Petruk, Ganna, et al.
Publicado: (2021)

Peroxidasin contributes to lung host defense by direct binding and killing of gram-negative bacteria
por: Shi, Ruizheng, et al.
Publicado: (2018)

The Network of Colonic Host Defense Peptides as an Innate Immune Defense Against Enteropathogenic Bacteria
por: Blyth, Graham A. D., et al.
Publicado: (2020)

Structural basis for endotoxin neutralisation and anti-inflammatory activity of thrombin-derived C-terminal peptides
por: Saravanan, Rathi, et al.
Publicado: (2018)

Chemotactic response of monocytes to thrombin
Publicado: (1983)

Thrombin and Plasmin Alter the Proteome of Neutrophil Extracellular Traps
por: Lim, Chun Hwee, et al.
Publicado: (2018)

The role of bacterial transport systems in the removal of host antimicrobial peptides in Gram-negative bacteria
por: Blair, Jessica M A, et al.
Publicado: (2022)

Systemic Activation of TLR3-Dependent TRIF Signaling Confers Host Defense against Gram-Negative Bacteria in the Intestine
por: Ruiz, Jose, et al.
Publicado: (2016)

Systematic Review of Membrane Components of Gram-Positive Bacteria Responsible as Pyrogens for Inducing Human Monocyte/Macrophage Cytokine Release
por: Rockel, Christoph, et al.
Publicado: (2012)

Antimicrobial Peptides Targeting Gram-Positive Bacteria
por: Malanovic, Nermina, et al.
Publicado: (2016)

Selective protein aggregation confines and inhibits endotoxins in wounds: Linking host defense to amyloid formation
por: Petrlova, Jitka, et al.
Publicado: (2023)

Macrophage defense mechanisms against intracellular bacteria
por: Weiss, Günter, et al.
Publicado: (2015)

Host Defense Proteins and Peptides with Lipopolysaccharide-Binding Activity from Marine Invertebrates and Their Therapeutic Potential in Gram-Negative Sepsis
por: Solov’eva, Tamara Fedorovna, et al.
Publicado: (2023)

Tenebrio molitor Spätzle 1b Is Required to Confer Antibacterial Defense Against Gram-Negative Bacteria by Regulation of Antimicrobial Peptides
por: Bae, Young Min, et al.
Publicado: (2021)

How Symbiotic Bacteria Survive Host Defenses
por: Meadows, Robin
Publicado: (2011)

Oncolytic Activities of Host Defense Peptides
por: Al-Benna, Sammy, et al.
Publicado: (2011)

Reassessing the Host Defense Peptide Landscape
por: Haney, Evan F., et al.
Publicado: (2019)

The future of recombinant host defense peptides
por: Roca-Pinilla, Ramon, et al.
Publicado: (2022)

Host Defense Peptides LL-37 and Lactoferrin Trigger ET Release from Blood-Derived Circulating Monocytes
por: Schwäbe, Frederic V., et al.
Publicado: (2022)

Host–Pathogen Interactions of Marine Gram-Positive Bacteria
por: Gnanagobal, Hajarooba, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_hpsmmifmj7u9nhmn10310f1hp6